Home >Pharmaceutical > alpha,alpha,alpha-Trifluoro-o-cresol
- Chemical Name: alpha,alpha,alpha-Trifluoro-o-cresol
- CAS No.: 444-30-4
Factory supply alpha,alpha,alpha-Trifluoro-o-cresol 444-30-4 with low price
- Molecular Formula: C7H5F3O
- Molecular Weight: 162.111
- Appearance/Colour: solid
- Vapor Pressure: 3.48mmHg at 25°C
- Melting Point: 45-46 °C(lit.)
- Refractive Index: 1.457
- Boiling Point: 147.5 °C at 760 mmHg
- PKA: 8.95(at 25℃)
- Flash Point: 65.6 °C
- PSA： 20.23000
- Density: 1.335 g/cm3
- LogP: 2.41100
alpha,alpha,alpha-Trifluoro-o-cresol(Cas 444-30-4) Usage
InChI:InChI=1/C7H5F3O/c8-7(9,10)5-3-1-2-4-6(5)11/h1-4,11H
444-30-4 Relevant articles
Cross-Coupling through Ag(I)/Ag(III) Redox Manifold
Demonti, Luca,Mézailles, Nicolas,Nebra, Noel,Saffon-Merceron, Nathalie
supporting information, p. 15396 - 15405 (2021/10/12)
In ample variety of transformations, the...
Method for hydrolyzing diarylether compound to generate aryl phenol compound
-
Paragraph 0111-0114, (2021/09/29)
The invention discloses a method for hyd...
Aerobic photooxidative hydroxylation of boronic acids catalyzed by anthraquinone-containing polymeric photosensitizer
Chen, Yang,Ding, Aishun,Hu, Jianhua
, p. 7927 - 7932 (2020/03/11)
We report herein the synthesis of a poly...
Photoinduced Hydroxylation of Organic Halides under Mild Conditions
Cai, Yue-Ming,Xu, Yu-Ting,Zhang, Xin,Gao, Wen-Xia,Huang, Xiao-Bo,Zhou, Yun-Bing,Liu, Miao-Chang,Wu, Hua-Yue
supporting information, p. 8479 - 8484 (2019/10/16)
Presented in this paper is photoinduced ...
444-30-4 Process route
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![1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-(trifluoromethyl)benzene](/upload/2026/6/e2d42e586176442399d00e63b59745a9_1f6e46a7-df82-4961-8bef-7bebfd07044e.png)
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1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-(trifluoromethyl)benzene
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444-30-4
2-(trifluoromethyl)phenol
| Conditions | Yield |
|---|---|
|
With
sodium cyanide;
In
ethanol; water;
at 50 ℃;
for 4h;
chemoselective reaction;
|
95.2%
|
-
-
392-83-6
o-trifluoromethylphenyl bromide
-
-
444-30-4
2-(trifluoromethyl)phenol
| Conditions | Yield |
|---|---|
|
With
cesiumhydroxide monohydrate; bis[(trimethylsilyl)methyl](1,5-cyclooctadiene)palladium(II); 2-((di-adamantan-1-yl)phosphaneyl)-1-(2,6-diisopropylphenyl)-1H-imidazole;
In
tetrahydrofuran;
at 24 ℃;
for 20h;
Inert atmosphere;
|
67%
|
|
With
oxygen; triethylamine; sodium iodide;
In
acetonitrile;
at 32 ℃;
for 24h;
Schlenk technique;
UV-irradiation;
|
50%
|
444-30-4 Upstream products
-
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-
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444-30-4 Downstream products
-
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-
62489-48-9
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-
149209-47-2
2-[2-(trifluoromethyl)phenoxy]tetrahydro-2H-pyrane
-
136539-10-1
3-(Trifluoromethyl)phenyl 2-Chloro-4-(trifluoromethyl)-5-thiazolylcarbamate