- Chemical Name: 2-(CYANOMETHYL)BENZOIC ACID
- CAS No.: 6627-91-4
2-(CYANOMETHYL)BENZOIC ACID 6627-91-4 with purity >99% Low price in stock
- Molecular Formula: C9H6NO2-
- Molecular Weight: 161.16
- Vapor Pressure: 1.84E-05mmHg at 25°C
- Melting Point: 126 °C
- Boiling Point: 348.8°Cat760mmHg
- PKA: 3.66±0.36(Predicted)
- Flash Point: 164.8°C
- PSA： 61.09000
- Density: 1.257g/cm3
- LogP: 1.45088
2-(CYANOMETHYL)BENZOIC ACID(Cas 6627-91-4) Usage
|
Purification Methods |
Crystallise the nitrile (with considerable loss) from *benzene, glacial acetic acid or H2O. The methyl ester has m 47-48o (from *C6H6). [Price & Rogers Org Synth Coll Vol III 174 1955, Beilstein 9 H 859, 9 II 618, 9 III 4267.] |
InChI:InChI=1/C9H7NO2/c10-6-5-7-3-1-2-4-8(7)9(11)12/h1-4H,5H2,(H,11,12)/p-1
6627-91-4 Relevant articles
Synthesis and biological evaluation of 3-aminoisoquinolin-1(2H)-one based inhibitors of the dual-specificity phosphatase Cdc25B
George Rosenker, Kara M.,Paquette, William D.,Johnston, Paul A.,Sharlow, Elizabeth R.,Vogt, Andreas,Bakan, Ahmet,Lazo, John S.,Wipf, Peter
, p. 2810 - 2818 (2015/03/04)
The cell division cycle 25B dual specifi...
ISOQUINOLINE AMINOPYRAZOLE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CANCER
-
Page/Page column 63-64, (2008/06/13)
Objects of the present invention are the...
A Convenient Synthesis of 2-Acylphenylacetonitriles
Canepa, Alicia S.,Bravo, Rodolfo D.
, p. 579 - 588 (2007/10/03)
The reaction of 2-cyanomethylbenzoyl chl...
Hydroformylation
-
Page 19, (2010/02/08)
The present invention relates to a proce...
6627-91-4 Process route
-
-
80070-33-3
2-Hydroxyimino-1-indanon
-
-
6627-91-4
2-cyanomethylbenzoic acid
| Conditions | Yield |
|---|---|
|
2-Hydroxyimino-1-indanon;
With
sodium hydroxide;
In
water;
at 50 ℃;
With
p-toluenesulfonyl chloride;
In
water;
With
hydrogenchloride;
In
water;
pH=3 - 4;
|
74%
|
-
-
19821-21-7
(2-carbethoxyphenyl)acetonitrile
-
-
6627-91-4
2-cyanomethylbenzoic acid
| Conditions | Yield |
|---|---|
|
With
sodium hydroxide;
at 40 ℃;
for 5h;
|
94%
|
6627-91-4 Upstream products
-
87-41-2
2-benzofuran-1(3H)-one
-
151-50-8
potassium cyanide
-
51050-54-5
3-Chloroisocoumarin
-
15028-10-1
indan-1,2-dione-2-oxime
6627-91-4 Downstream products
-
5597-04-6
2-cyanomethylbenzoic acid methyl ester
-
75227-06-4
2-[2-(2-chloro-phenyl)-1-cyano-vinyl]-benzoic acid
-
56114-27-3
2-(1-cyano-2-phenyl-vinyl)-benzoic acid
-
14961-34-3
diethyl homophthalate